Potential anticancer agents, XI. X-ray structure determination of acantholide.

نویسندگان

  • H Lotter
  • H Wagner
  • A A Saleh
  • G A Cordell
  • N R Farnsworth
چکیده

The X-ray structure of acantholide, a melampolide sesquiterpene lactone from Acanthospermum glabratum (DC.) Willd. was determined by the aid of direct methods. The compound was cytotoxic but displayed no antitumor activity. Evaluation of the X-ray and NMR data indicated that the same conformation exists in the solid state as in solution.

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عنوان ژورنال:
  • Zeitschrift fur Naturforschung. Section C, Biosciences

دوره 34 9-10  شماره 

صفحات  -

تاریخ انتشار 1979